Development & manufacturing using stick-pack technology

Stick-pack packaging offers a single-dose format suitable for liquid healthcare products for oral and topical administration.

It protects the contents from moisture, oxygen, and light. Thanks to its small size and compactness, this single-dose product is practical, easy to use, and convenient for daily use.

Stérile
Material: An assembly of several components designed to ensure product stability over time
Volume_Filling (1)
Filling volume: 1 to 15 ml
personnalisation
Customization: shapes, sizes, resins, and colors. Marking options: inkjet printing, laser, embossing, screen printing, labeling, or stamping.
Stick- Pack
goutte liquide
Viscosity: 1 to 1500 cP
solutions supensions
Types of formulations: solutions, suspensions, emulsions, gels
statut
Statuses: Medicines, Medical Devices, Food Supplements, Cosmetics

Benefits of Stick-Pack

Stick-pack

A precise, ready-to-use dose to improve patient health

Suitable for all therapeutic areas (eg.: analgesics, gastroenterology, cardiovascular diseases, central nervous system, orphan diseases, cough and cold, etc.).

Benefits:

    • Safety of use
    • Precise dose delivery
    • Ready-to-use, robust, and easy to transport
    • Good product preservation
    • Improved formulation (taste masking and reduced or no preservatives)
    • Patients can purchase individual Stick-Packs

 

Single-dose Stick-Pack packaging helps preserve products that are sensitive to oxygen (preparation and filling under nitrogen) or light, thanks to its barrier effect. Other formulation options are also available, such as taste masking and preservative-free formulation.

Manufacturing sites

Our sites are regularly inspected by different authorities including: ANSM (France), EU GMP (Europe), the FDA (United States), ANVISA (Brazil), Russia, etc., and most authorities worldwide.

Out-licensing - our turnkey documentation and products in Stick-Pack packaging

 Table: Out-licensing - our turnkey documentation and products in Stick-Pack packaging
Liquid stick-packs Volume Category Status Dossier Country
Dextromethorphan [preservative-free] 15mg 5 ml Cough and cold Medicine Dossier available Contact Us
Oxomemazine [sugar-free] 0.33mg/mL 10 ml Cough and cold Medicine MA available FR
Sodium alginate 10 ml Gastroenterology Medicine MA available FR
Paracetamol [preservative-free] 500mg and 1000mg (500mg/5mL) 5, 10 ml Fever, pain Medicine MA available BR
Paracetamol for children [paraben-free; sugar-free] 200mg & 300mg 8.3, 12.5 ml Fever, pain Medicine Dossier available Contact Us
Mouthwash 10 ml Oral health Cosmetic Dossier available Contact Us
Paracetamol 0.500 g / Vitamin C 0.200 g / Pheniramine maleate 0.025 g 1.483 g Cough and cold Medicine MA available Contact Us
Ambroxol hydrochloride 30 mg/5 ml 5 mL Cough and cold Medicine Dossier available Contact Us

End-to-end support from the initial phases: from concept to product

Development

Formulation and analytical development, manufacture of clinical batches, stability studies, and expertise in ophthalmic development.

Manufacturing

From technology transfer to industrial manufacturing, from small clinical batches to commercial volumes.

Out-licensing

Access medicines and medical devices that are ready to be registered and marketed.

Got questions? - Consult our FAQ

Unither stands out as a global leader thanks to:

  • Three dedicated manufacturing sites (France, USA, Brazil) ensuring supply continuity and international reach
  • More than 500 million sticks produced annually with high‑speed FFS technology
  • Deep formulation expertise (Bordeaux development unit) for stability, taste masking, and API compatibility
  • Strong packaging partnerships enabling custom, high‑performance—and soon recyclable—films
  • Full regulatory support including IMPD/IND, MA dossiers, variations, and agency queries

Few CDMOs match this combination of scale, technical depth, and proven reliability.

Yes. Thanks to its turnkey development services, pilot lines, and experience with hundreds of formulations, Unither can significantly shorten timelines by:

  • Conducting feasibility, scale‑up, and stability programs in-house
  • Offering ready‑to‑license stick‑pack products
  • Managing regulatory strategy and documentation
  • Ensuring rapid industrial transfer across global sites

This makes Unither a partner capable of supporting your project from concept to market launch with speed and reliability.

Stick‑packs accommodate a wide range of products:

  • Oral solutions, micro‑emulsions, and suspensions
  • Pediatric medicines
  • Pain relief products
  • ENT formulations
  • Cosmetic liquids such as mouthwash
  • Nutraceutical liquids

Unither’s lines support volumes from 2 to 15 mL, enabling both OTC and Rx applications.

Unither has mastered the transfer of manufacturing processes between its sites, including the production of registration batches.
For example, as part of a treatment for Charcot-Marie-Tooth disease type 1A (CMT1A), Unither managed the industrial transfer to the United States, the manufacture of registration batches in liquid stick packs, and the launch of the stability studies required for filing an FDA New Drug Application (NDA).

Stick‑pack technology is a single‑dose packaging format for liquids, gels, or semi‑solid formulations. It offers precise dosing, easy administration, and portability, making it ideal for populations like children, seniors, and on‑the‑go adults.
Unlike bottles, stick‑packs eliminate dosing errors and reduce contamination risks.
Unither pioneered liquid stick‑packs more than 30 years ago, making it one of the most experienced partners worldwide for this format.

Unither performs extensive container–content compatibility studies, working directly with film suppliers to engineer materials that:

  • Protect sensitive APIs
  • Offer low extractables/leachables (e.g., StayClean films)
  • Prevent delamination and corrosion (critical for alcohol‑based solutions)
  • Recyclable laminates

This co‑development approach ensures each product receives a tailored, stability‑optimized packaging solution, not an off‑the‑shelf compromise.

Liquid stick packs are the preferred choice when dose accuracy and patient compliance are key concerns. The dose is pre-measured, eliminating errors associated with spoons, pipettes, or droppers. They are particularly suitable for children, the elderly, or patients with cognitive impairments, as well as in situations where tracking medication intake is important (with an empty stick serving as proof of use).
The Unither teams will help you choose the most suitable format (stick-pack or bottle) based on your product and your market.

Yes. Single-dose packaging prevents contamination after opening. Unither can therefore develop formulations without preservatives or with reduced preservative levels, while ensuring microbiological purity until use.