Blow-Fill-Seal: Sterile, Single-Use, Practical

Looking to simplify sterile product development?


Discover how Blow-Fill-Seal (BFS) technology accelerates innovation, enhances sterility, and reduces reliance on preservatives — across ophthalmology, ENT, biologics, and more.

This whitepaper shows how Blow-Fill-Seal (BFS) technology is transforming the development of sterile, preservative-free, single-use pharmaceuticals. From ophthalmic and respiratory treatments to complex biologics, BFS offers a scalable, cost-effective, and patient-safe alternative to traditional aseptic filling.
Written for pharmaceutical developers and technical teams, it combines technical insights, expert contributions, and a real-world case study to help you evaluate BFS for your next project.

What you’ll learn:

  • Key principles and advantages of BFS technology in sterile manufacturing
  • Technical considerations for formulation and device integration
  • A step-by-step case study: developing an injectable via BFS
  • Regulatory and operational considerations for successful implementation

Written for: Pharmaceutical developers, formulators, and technical leads.

Contributors: Unither’s experts in R&D, operations, quality, regulatory, and supply chain.

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